Quorum Sensing Inhibitory Activity of Giganteone A from Myristica cinnamomea King against Escherichia coli Biosensors.

نویسندگان

  • Yasodha Sivasothy
  • Thiba Krishnan
  • Kok-Gan Chan
  • Siti Mariam Abdul Wahab
  • Muhamad Aqmal Othman
  • Marc Litaudon
  • Khalijah Awang
چکیده

Malabaricones A-C (1-3) and giganteone A (4) were isolated from the bark of Myristica cinnamomea King. Their structures were elucidated and characterized by means of NMR and MS spectral analyses. These isolates were evaluated for their anti-quorum sensing activity using quorum sensing biosensors, namely Escherichia coli [pSB401] and Escherichia coli [pSB1075], whereby the potential of giganteone A (4) as a suitable anti-quorum sensing agent was demonstrated.

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عنوان ژورنال:
  • Molecules

دوره 21 3  شماره 

صفحات  -

تاریخ انتشار 2016